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Neurologic adverse events in pediatric patients treated with nelarabine 650 mg/m2 intravenously for 5 consecutive days, repeated every 21 days21
| Nervous system disorders |
Patient population (n = 84) |
|
|---|---|---|
| Grade 3/4 (%) | All Grades (%) | |
| Headache | 6 | 17 |
| Peripheral neurologic disorders | 7 | 12 |
| Lowered consciousness | 2 | 7 |
| Peripheral neurologic disorders | 7 | 12 |
| Hypoesthesia | 4 | 6 |
| Seizures | 6 | 6 |
| Motor dysfunction | 1 | 4 |
| Nervous system disorder | 0 | 4 |
| Paresthesia | 1 | 4 |
| Tremor | 0 | 4 |
| Ataxia | 1 | 2 |
