Table 1.

Revised International Autoimmune Hepatitis Group Scoring System for the Diagnosis of Autoimmune Hepatitis (AIH)

Clinical feature	Score
Reproduced from Alvarez F, et al.11
Female gender	+2
ALP:AST ratio <1.5 1.5–3.0 >3.0	+2 0 –2
Serum globulin or IgG above normal >2.0 1.5–2.0 1.0–1.5 <1.0	+3 +2 +1 0
ANA, SMA, LKM1 >1:80 1:80 1:40 <1:40	+3 +2 +1 0
Illicit drug use history Positive Negative	–4 +1
Average alcohol intake daily <25 g/day >60 g/day	+2 –2
Histologic findings Interface hepatitis Lymphoplasmacytic infiltrate Rosette formation None of the above Biliary changes Other changes	+3 +1 +1 –5 –3 +2
Other autoimmune disease	+2
AMA positivity	–4
Hepatitis viral markers Positive Negative	–3 +3
Aggregate score without treatment Definite AIH Probable AIH	>15 10–15

ALP=

alkaline phosphatase;

AST=

aspartate aminotransferase;

IG=

immunoglobulin;

ANA=

antinuclear antibody;

SMA=

smooth muscle antibody;

LKM1=

liver kidney microsomal antibody;

AMA=

antimitochondrial antibody.