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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Epigenomics. 2009 Oct;1(1):111–117. doi: 10.2217/epi.09.11

Table 3.

Transgenerational versus multigenerational phenotypes and toxicology.

Phenotype Exposure Definition
Multigenerational Direct Coincident direct exposure of multiple generations to
an environmental factor or toxicant promoting a
toxicology in the multiple generations exposed
Transgenerational None, except the initial
(ancestral) generation
After the initial exposure, the transgenerational
phenotype is only transmitted through the germline
in the absence of direct exposure