Fig. 12.

β-Oxidation of palmitic acid by gastrocnemius muscle of iPLA₂γ-KO and WT mice fed SC or WD. WT (light bars) and iPLA₂γ-KO (dark bars) mice were fed SC or WD as in Fig. 1, and at age 6 mo gastrocnemius muscle specimens were obtained and ¹⁴CO₂ production from [¹⁴C]palmitate by muscle homogenates was determined as described in experimental procedures and elsewhere (16) and expressed as nmol CO₂/mg muscle protein. Mean values ± SE are indicated (n = 12). *Significantly (P < 0.05) greater value in genotype comparisons; x, significantly greater weight in diet comparisons.