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Changes in silent SIRT1 (A), PGC-1α (B), cytochrome c (C), and cytochrome c oxidase IV (COX-IV)-subunit I protein content (D) in the RG muscle. Values are means ± SE (n = 5–8). #Significant difference between 20- and 40-wk values within respective animal group (P < 0.05). †Significantly different from OLETF-SED at respective age (P < 0.05). *Significantly different from LETO-SED at respective age (P < 0.05). AU, arbitrary units.
