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Zinc deficiency increases caspase-3 activity in the lung in response to CLP. Identical lung specimens as described previously were processed and subjected to analysis for caspase-3 activity at 24 h after CLP in response to zinc deficiency as well as supplementation (n = 5 per group; *Zn−/CLP vs. Ctrl/CLP, P < 0.05; ‡Zn+/CLP vs. Zn−/CLP, P < 0.05).
