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Role of taxol in the development of ventilator-induced lung injury (VILI). Mice were treated with vehicle or taxol (3.75 × 10−7 mol/kg iv) before TRAP6 instillation (1.5 × 10−5 mol/kg it) and mechanical ventilation at HTV (30 ml/kg, 4 h). BAL cell count and protein concentration were determined as described in materials and methods. Data are expressed as means ± SD of 4 independent experiments; *P < 0.05.
