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. 2010 Apr 2;298(6):H1842–H1849. doi: 10.1152/ajpheart.01236.2009

Table 2.

Deactivation rates of WT and ΔY475 hERG in cardiomyocytes and HEK-293 cells at −50 mV

WT hERG
 ΔY475 hERG
Tfast Tslow Tfast Tslow
Neonatal mouse cardiomyocytes 273.9 ± 17.5* 1,740.7 ± 163.9* 64.8 ± 9.4* 266.3 ± 53.4*
HEK-293 cells 586.7 ± 47.7* 3,793.1 ± 333.1* 97.3 ± 4.3* 400.0 ± 24.9*
Percent change 213.9 217.9 150.2 150.2

Values are means ± SE. Tfast, fast deactivation rate (in ms); Tslow, slow deactivation rate (in ms); percent change = HEK-293 cells/cardiomyocytes.

*

P < 0.05, cardiomyocyte data compared with respective HEK-293 cell data.