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Concentration-response curves for the sodium nitroprusside (SNP)-induced relaxation of isolated abdominal aortic rings obtained from LSED, OPA, and OSED rats at 13, 20, and 40 wk of age. Data were obtained in the absence (A, C, and E) or presence (B, D, and F) of l-NNA (3 e−4 M). See methods for more details. Data are means ± SE; n = 6–8 rats per group or treatment combination. *P < 0.05, 40 vs. 13 wk; #P < 0.05, 40 vs. 20 wk.
