Schematic of experimental protocol. Thick horizontal lines show duration of cardiac arrest, dark gray box represents cardiopulmonary resuscitation (CPR) interval, and light gray area represents interval of therapeutic hypothermia (TH, 30 ± 0.5°C). At 1 h post-return of spontaneous circulation (ROSC), animals were rewarmed to 37 ± 0.5°C. NT, normothermia.