Table 2.
Akt1+/− group baseline and resuscitation period characteristics
| Akt1NT+/− | Akt1TH+/− | |
|---|---|---|
| n | 8 | 10 |
| Baseline | ||
| Body weight, g | 30.9 ± 4.9 | 30.5 ± 3.1 |
| Heart rate, beats/min | 267 ± 34 | 276 ± 23 |
| LVPmax, mmHg | 101.8 ± 14.0 | 95.9 ± 8.8 |
| dP/dtmax, mmHg/ms | 7.7 ± 1.3 | 7.7 ± 1.2 |
| τ, ms | 9.7 ± 1.2 | 8.7 ± 1.1 |
| Stroke volume, μl | 11.3 ± 2.0 | 12.1 ± 3.2 |
| Cardiac output, ml/min | 3.0 ± 0.5 | 2.9 ± 0.7 |
| PetCO2, mmHg | 37.1 ± 5.68 | 37.8 ± 5.00 |
| CPR | ||
| CC rate, beats/min | 345 ± 44 | 358 ± 36 |
| DBP, mmHg | 21.4 ± 8.8 | 22.4 ± 7.8 |
| PetCO2, mmHg | 24.5 ± 5.6 | 20.8 ± 4.7 |
| ROSC, n (%) | 8 (100) | 8 (80) |
| Time to ROSC*, s | 137 ± 46 | 147 ± 59 |
Values are means ± SD; n, number of mice.
*
Calculated for subset of animals achieving ROSC.