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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Curr Genet. 2009 Dec 31;56(2):121–137. doi: 10.1007/s00294-009-0285-3

Table 2.

Drug and ion sensitivities of uncovered hhy mutants

Strain YPD 1M
NaCl
1M
KCl
0.5 M
KCl
0.5 mM
CaCl2
0.2 mM
CaCl2
10 mM
MnCl2
4 mM
ZnCl2
pH
2.5
pH
8.0
20 nM
rapamycin
20 mM
caffeine
WT +++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++ +++
hhy1 +++ +++ +++ +++
drs2 +++ +++ +++ +++ ++ ++ ++ +++ +++ ++
luv1 +++ +++ +++ +++ +++ +++
sbh2 ++ ++ ++ ++ ++ ++ ++ ++ ++
sac1 +++ ++ +++ +++ +++ +++ +++ ++ ++
arf1 ++ ++ ++ ++ ++ ++ ++ ++ ++ ++
paf1 +++ +++ +++ +++ +++ +++ ++ +++ + ++
dhh1 +++ ++ +++ +++ +++ +++ ++ +++ +++ ++
vps45 +++ ++ +++ +++ +++ +++ ++
sac2 +++ ++ +++ +++ +++ +++
vps34 ++ ++ ++ ++ ++ ++
tpd3 ++ + + + ++ +
chc1 +++ +++ +++ +++ +++ +++
bud32 +++ +++ +++ +++ +++ +++ +++

BY4742 (WT) and 14 mutants were grown on YPD and selective media with the indicated concentrations. Following 48–96-h growth, colony number and size on plates were scored as follows: +++ strong growth; ++ moderate growth; ∓ weak growth; − no growth