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. Author manuscript; available in PMC: 2010 Jun 16.
Published in final edited form as: Neurobiol Dis. 2008 Jul 11;32(2):229–242. doi: 10.1016/j.nbd.2008.06.018

Figure 3. Tyrosine hydroxylase (TH, blue) and MHC class II molecule (MHC II, brown) immunostained, coronal brain sections in the dopamine-depleted striatum.

Figure 3

A) Sham treated rats showed an absence of TH innervation and sparse MHC class II expression. B) Allografted rats sacrificed at 10 weeks post-grafting (G10) showed numerous TH+ cells as well as moderate MHC class II expression at the site of the graft. C) Allografted rats sacrificed on week 21 post-grafting (G21) showed abundant TH+ cells and a reduced expression MHC class II expression compared to G10. D) Allografted rats receiving peripheral spleen cell injections and sacrificed at 21 weeks (G21 + spleen) showed some remaining TH+ cells and robust MHC class II expression. Scale bar in A represents 1mm and is valid for A–D.