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Schematic representation of contributions of the baroreflex vs. chemoreceptor reflex to the pressor response to bilateral carotid occlusion (BCO) in young (∼3 mo) vs. old (∼18 mo) and 5–8 mo WT and ASIC2 KO mice. The relatively small contribution of the chemoreflex in WT and in young mice is increased significantly in ASIC2 KO mice and in old mice as the baroreflex components decline (see Refs. 34 and 64). BP, blood pressure.
