Table 3.
Effect of CCK-8 on chow intake by deprived mice
| Genotype | Age, mo | n | Body Weight, g | Intake After Vehicle, g | Intake After CCK, 3 μg/kg | Intake After CCK, 6 μg/kg |
|---|---|---|---|---|---|---|
| MC3R−/− | 3–4 | 5 | 21.9 ± 1.2 | 0.53±.04 | 0.53±.07 | 0.38±.13 |
| MC3R−/− | 7–8 | 5 | 26.0 ± 0.9 | 0.72±.09 | 0.48±.10 | 0.47±.06 |
| MC3R+/+ | 3–4 | 4 | 18.9 ± 1.2 | 0.69±.06 | 0.68±.07 | 0.35±.11 |
| MC3R+/+ | 7–8 | 10 | 23.6±.08 | 0.81±.04 | 0.52±.05 | 0.35±.06 |
| MC4R−/− | 3–4 | 7 | 42.5 ± 1.2 | 0.50±.05 | 0.40±.05 | 0.24±.03 |
| MC4R−/− | 10–11 | 5 | 57.1 ± 4.6 | 0.76±.03 | 0.57±.08 | 0.28±.03 |
| MC4R+/+ | 3–4 | 7 | 25.6 ± 0.6 | 0.67±.04 | 0.56±.05 | 0.41±.02 |
Values are expressed as means ± SE. Body weights are the mean of 3 wk, predeprivation.