Table 2.
Summary of genes, Nox genes, and differentially expressed genes from oxidant-stress PCR array at 35 days post-IR injury in gracilis arteries
| Unigene ID | RefSeq | Symbol/Abbreviation | Name | Log2, ratio |
|---|---|---|---|---|
| Rn.40511 | NM_021588 | Mb | Myoglobin | −3.75* |
| Rn.17990 | NM_130748 | Slc38a4 | Solute carrier protein 38a4 | −2.21*† |
| Rn.25565 | XM_214130 | Zmynd17 | Zinc Finger MYND type containing 17 | −1.77*† |
| Rn.9902 | NM_013167 | UCP3 | Uncoupling protein 3 | −1.34* |
| Rn.162651 | XM_231042 | Noxa1 | NADPH oxidase activator 1 | ND |
| Rn.137764 | XM_220221 | Noxo1 | NADPH oxidase organizer 1 | ND |
| Rn.14744 | NM_053524 | Nox4 | NADPH oxidase 4 | 0.63 NS |
Values expressed as natural log of ratio-derived ΔΔCt values; positive values represent enhanced expression vs. sham-operated control; negative values represent suppressed expression vs. sham-operated control. ND, not detectable consistently in both experimental and control samples.
*
Genes considered differentially expressed as defined as ratio > mean ±2*SD; derived from the distribution of ratios averaged over 3 separate comparisons; the value was ± 1.34.
†
Despite inclusion on this pathway-focused array, there are no substantive reports indicating the role of these genes in mediating oxidant stress.