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Suramin (SUR), a P2Y2 receptor antagonist, blocks UTP-induced resensitization of TRPV1. A: representative recording showing that suramin (30 μM) blocks the resensitization of TRPV1 caused by UTP. B: mean data of experiments illustrated in A. Data are expressed as means ± SE; n = 6 neurons from 5 rats. *P < 0.01 vs. first application of capsaicin.
