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. Author manuscript; available in PMC: 2011 May 27.
Published in final edited form as: Neuron. 2010 May 27;66(4):550–559. doi: 10.1016/j.neuron.2010.04.024

Figure 5.

Figure 5

Calcium blocks CaN*/CaMKII*-induced EPSC run up. (A) EPSC amplitudes in neurons infused with both CaN* and CaMKII* and held at −40 mV (open circles) and at −70 mV (closed circles). EPSC amplitudes were normalized to the first 10 measurements at each voltage. Scale: 200 pA, 10 ms. (B) EPSCs recorded at −40 mV in neurons infused with 10 mM BAPTA, CaN* and CaMKII*. (C) EPSCs at −40 mV in neurons infused with CaN* and CaMKII* during bath application of 10 μM nimodipine. (D) Mean EPSC amplitudes at −40 mV for neurons infused with both CaN* and CaMKII* in control solutions (open triangles; n = 9), with BAPTA (circles; n = 7) or in nimodipine (closed triangles; n = 6).