Figure 1. Effect of CLP on ex-vivo cytokine expression by control and LPS-stimulated PM.

Cytokine mRNA expression was determined 4 hrs post vehicle or LPS administration by real-time PCR and expressed as fold increase over unstimulated sham PM. Panel E represents TNF-α expression from PM collected at 1, 3, and 7 days post sham surgery or CLP. n = 5 per condition, *p<0.05 as compared to sham counterpart.