TABLE 1.

Treatment Schedule of Animals

Animal identification	Treatment	Total no. of doses
01–05	Vehicle	1
06–10	Low dose	1
11–15	High dose	1
16–20	Vehicle	3
21–25	Low dose	3
26–30	High dose	3
26–30	Vehicle	14
31–35	Low dose	14
36–40	High dose	14

Note. Urine was collected from animals no. 31–45 after 1, 3, and 12 days of dosing.