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. 2010 Apr 12;116(1):113–121. doi: 10.1093/toxsci/kfq104

FIG. 6.

FIG. 6.

SST and SG cytotoxicity in vitro. SST and SG both cause a significant dose response in both strains of mice (p = 0.0001). SST and SG are significantly more cytotoxic to C57BL/6J AMs than to BALB/c AMs (*p = 0.02 and **p = 0.059 respectively)—75,000 live cells plated per well for all wells. Data are shown as mean ± SE. Graphs are on a log-log scale. (A) Dose (SST [μg/ml SG equivalents]) verses live cells as a percent of baseline (baselines are calculated as the total number of cells in matched wells with RPMI-1640). Slopes from 0.01–0.5 μg/ml SG equivalents of SST for C57BL/6J (–0.41) are significantly different from BALB/c (–0.23). (B) Dose (μg SG/ml RPMI 1640) verses live cells as a percent of baseline (baselines are calculated as the total number of live and dead cells in matched wells with no SST). Slopes from 0.03–0.7 μg/ml SG for C57BL/6J (–0.27) are significantly different from BALB/c (–0.18).