. Author manuscript; available in PMC: 2010 Dec 1.

Published in final edited form as: Nat Genet. 2009 Dec;41(12):1290–1294. doi: 10.1038/ng.486

Table 2.

Effect of -35 on AIDS progression

Outcome	Genotype	n	HR (95% CI)	P value
CD4 <200	CC vs. TT	114 vs. 251	0.62 (0.43–0.90)	0.01
	CT vs. TT	367 vs. 251	0.89 (0.71–1.12	0.31
	CC vs. CT	114 vs. 367	0.70 (0.50–0.99)	0.05
	CX^a vs. TT	481 vs. 251	0.84 (0.67–1.04)	0.11
AIDS 1987	CC vs. TT	117 vs. 265	0.52 (0.35–0.78)	0.001
	CT vs. TT	381 vs. 265	0.68 (0.53–0.86)	0.002
	CC vs. CT	117 vs. 381	0.75 (0.51–1.10)	0.14
	CX vs. TT	498 vs. 265	0.65 (0.51–0.82)	0.0003
Death	CC vs. TT	117 vs. 265	0.43 (0.26–0.70)	0.001
	CT vs. TT	381 vs. 265	0.64 (0.49–0.85)	0.002
	CC vs. CT	117 vs. 381	0.64 (0.40–1.02)	0.06
	CX vs. TT	498 vs. 265	0.60 (0.46–0.79)	0.0003

n = 763; HR, hazard ratio; CI, confidence interval. Age of seroconversion, B*27, B*57 and B*35Px were used as covariates and data stratified by cohort.

CX = CC/CT genotypes.