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. 2010 Mar 15;14(2):R31. doi: 10.1186/cc8908

Table 2.

Changes of cerebral and spinal perfusion pressures during the four experimental phases (T1 to T4).

T1
(baseline)
T2
(IAP = 20 mmHg)
T3
(IAP = 45 mmHg)
T4
(desufflation)
MAP 85.8 ± 9.62 79.8 ± 11.7 86.8 ± 15.73 84.6 ± 7.37
p 0.186 (T1 vs. T2) 0.297(T2 vs. T3) 0.625 (T3 vs. T4)
ICP 18.7 ± 7.57 25.4 ± 7.79 26.8 ± 9.17 15.3 ± 3.65
p <0.001 (T1 vs. T2) 0.485 (T2 vs. T3) <0.001 (T3 vs. T4)
CPP 67.1 ± 13.81 54.4 ± 9.77 60 ± 16.54 69.3 ± 8.38
p 0.013 (T1 vs. T2) 0.392 (T2 vs. T3) 0.057 (T3 vs. T4)
ISP 13.2 ± 3.26 25.4 ± 8.36 22.3 ± 8 12.3 ± 3.86
p 0.001 (T1 vs. T2) 0.375 (T2 vs. T3) 0.005 (T3 vs. T4)
SPP 72.6 ± 10.95 54.4 ± 10.6 64.5 ± 21.57 72.3 ± 7.42
p 0.002 (T1 vs. T2) 0.198 (T2 vs. T3) 0.235 (T3 vs. T4)

CPP is calculated as mean arterial pressure (MAP) minus intracranial pressure (ICP), while SPP as MAP minus intraspinal pressure (ISP). All pressures are displayed as mean ± SD and expressed as mmHg. Statistical significances (p < 0.05) are marked with bold. IAP: intra-abdominal pressure.