Table 5.
Organ dysfunction patterns
| Characteristic | All patients (n = 542) |
Abdominal infection (n = 162) |
Respiratory infection (n = 380) |
P-value |
|---|---|---|---|---|
| Sepsis syndromes at any time during the ICU stay | ||||
| Severe sepsis | 449 (82.8%) | 128 (79.0%) | 321 (84.5%) | 0.12 |
| Septic shock | 241 (44.5%) | 81 (50.0%) | 160 (42.1%) | 0.09 |
| Procedures during ICU stay | ||||
| Mechanical ventilation | 437 (80.6%) | 129 (79.6%) | 308 (81.1%) | 0.70 |
| Hemofiltration | 69 (12.7%) | 29 (17.9%) | 40 (10.5%) | 0.02 |
| Hemodialysis | 27 (5.0%) | 8 (4.9%) | 19 (5.0%) | 0.97 |
| SOFA scores | ||||
| SOFA max | 8.4 ± 4.4 | 8.4 ± 4.8 | 8.4 ± 4.3 | 0.90 |
| SOFA mean | 5.6 ± 3.9 | 5.6 ± 4.0 | 5.6 ± 3.9 | 0.95 |
| Early organ failurea | ||||
| Renal | 174 (32.1%) | 62 (38.3%) | 112 (29.5%) | 0.04 |
| Respiratory | 286 (52.8%) | 79 (48.8%) | 207 (54.5%) | 0.22 |
| Coagulation | 64 (11.8%) | 28 (17.3%) | 36 (9.5%) | 0.01 |
| Hepatic | 33 (6.1%) | 7 (4.3%) | 26 (6.8%) | 0.26 |
| CNS | 132 (24.4%) | 16 (9.9%) | 116 (30.5%) | < 0.001 |
| Cardiovascular | 249 (45.9%) | 90 (55.6%) | 159 (41.8%) | 0.003 |
| Late organ failureb | ||||
| Renal | 74 (13.7%) | 16 (9.9%) | 58 (15.3%) | 0.09 |
| Respiratory | 56 (10.3%) | 17 (10.5%) | 39 (10.3%) | 0.93 |
| Coagulation | 16 (3.0%) | 7 (4.3%) | 9 (2.4%) | 0.21 |
| Hepatic | 16 (3.0%) | 8 (4.9%) | 8 (2.1%) | 0.07 |
| CNS | 27 (5.0%) | 8 (4.9%) | 19 (5.0%) | 0.97 |
| Cardiovascular | 30 (5.5%) | 6 (3.7%) | 24 (6.3%) | 0.22 |
| Organ failure any time | ||||
| Renal | 248 (45.8%) | 78 (48.1%) | 170 (44.7%) | 0.46 |
| Respiratory | 342 (63.1%) | 96 (59.3%) | 246 (64.7%) | 0.22 |
| Coagulation | 80 (14.8%) | 35 (21.6%) | 45 (11.8%) | 0.003 |
| Hepatic | 49 (9.0%) | 15 (9.3%) | 34 (8.9%) | 0.90 |
| CNS | 159 (29.3%) | 24 (14.8%) | 135 (35.5%) | < 0.001 |
| Cardiovascular | 279 (51.5%) | 96 (59.3%) | 183 (48.2%) | 0.01 |
CNS: Central nervous system; a, occurring within 48 hours of a diagnosis of sepsis;
b, occurring more than 48 hours after a diagnosis of sepsis