Table 1.
Patients, surgical procedure and survey characteristics, and levels of IL-6, CRP and cortisol on postoperative Day 1 (POD1)
| AAS patients (n = 20) |
CAS patients (n = 20) |
P-value | |
|---|---|---|---|
| Age (years) | 67.0 ± 2.9 | 73.9 ± 2.8 | ns |
| Male/female (n) | 17/3 | 13/7 | ns |
| Blood loss (mL) | 1,000 (400-3,500) | 100 (50-900) | < 10-4 |
| Fluid infusion (mL) | 4,500 (3,000-9,000) | 1,500 (1,000-3,000) | < 10-4 |
| Red blood cell transfusion | 1 (0 to 6) | 0 (0 to 2) | < 10-4 |
| Fresh-frozen plasma | 1 (0 to 4) | 0 | ns |
| Cell-saver | 2 (0 to 8) | 0 | ns |
| Operation duration (hours) | 2.5 (1.6 to 6.5) | 1.2 (1 to 2.5) | < 10-4 |
| Vascular clamping duration (minutes) | 50.5 (14 to 90) | 26 (12 to 45) | < 10-4 |
| Post-surgical complications (cardiac and/or respiratory) |
9 | 3 | 0.038 |
| Infection | 4 | 2 | ns |
| IL-6 pg/ml (POD1) | 142 ± 41 | 14 ± 3 | 0.004 |
| CRP pg/ml (POD1) | 132 ± 16 | 25 ± 4 | < 0.001 |
| Cortisol ng/ml (POD1) | 229 ± 44 | 157 ± 26 | 0.07 |
Results are provided either as the mean ± SEM or as the median (range).
Continuous values were compared by the Mann-Whitney test and frequencies or percentages were tested by the χ2 or Fisher exact test. P values are given for the comparison between AAS and CAS. ns: not significantly different.