Table 4.
Histological findings in IBS patients and controls
| Lesion | IBS patients (n = 466), n (%) |
Controls (n = 451), n (%) |
P value |
|---|---|---|---|
| Adenomas | 36 (7.7) | 118 (26.1) | <0.0001 |
| Hyperplastic polyps | 39 (8.4) | 52 (11.5) | NS |
| Colorectal adenocarcinoma |
0 (0.0) | 1 (0.2) | NS |
| IBD | 2 (0.4) | 0 | NS |
| Microscopic colitis | 7 (1.5) | N/Aa | N/A |
| Solitary rectal ulcer syndrome |
1 (0.2) | 1 (0.2) | NS |
IBD, inflammatory bowel disease; IBS, irritable bowel syndrome; NS, not significant.
a
Number of controls with microscopic colitis is not recorded, as those participants did not undergo systematic random colon mucosa biopsies.