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. Author manuscript; available in PMC: 2010 Jun 17.
Published in final edited form as: Science. 2010 Mar 19;327(5972):1515–1518. doi: 10.1126/science.1184245

Fig. 4.

Fig. 4

Spatial learning is attenuated at puberty: reversal by the stress steroid THP. (A) Spatial learning platform (shock zone, black sector). (B) Times for first entry of the shock zone. Pre-pub mice attained the longest entry times. Pre-pub, black square; +THP, open circle; Pub, black triangle; +THP, open triangle (*Pre-pub versus Pre-pub +THP, Pub, P < 0.05; *Pub versus Pub +THP, P < 0.05, Tukey’s test). Error bars indicate SE of the mean. (C) Time to reach criterion (120 s) indicated for each group (numbers, best entry time). Vehicle, white bars; THP, hatched bars. *P < 0.05 Pre-pub versus Pub; **P < 0.05 versus vehicle. (D) Longest first entry time for Pub +/+ and δ−/− mice after vehicle or THP (vehicle, white bars; THP, hatched bars). *P < 0.05 versus δ−/− vehicle; **P < 0.05 versus +/+ THP.