Table 1.
Pathway | Total # genes | Uw | Ux | Dw | Dx |
---|---|---|---|---|---|
Cell cycle | 46 | 12 | 20 | 8 | 6 |
Chromatin structure | 37 | 8 | 20 | 8 | 1 |
Translation | 59 | 18 | 22 | 7 | 12 |
Spermatogenesis | 32 | 10 | 12 | 9 | 1 |
Average gene expression ratios for genes involved in significantly regulated pathways are compared between Wt and Xpc-/- mice. The table shows the number of genes that are up or down regulated to a higher extent after B[a]P exposure in either genotype.
Uw, up regulated to a higher extent in Wt mice. Ux, up regulated to a higher extent in Xpc-/- mice. Dw, down regulated to a greater extent in Wt mice. Dx, down regulated to a greater extent in Xpc-/- mice.