Table 2.
Differentially regulated genes regarding the cell cycle process after B[a]P exposure.
| Symbol | Gene Name | Wt | Xpc-/- |
|---|---|---|---|
| Bin3 | bridging integrator 3 | 1.13 | 1.31 |
| Brca2 | breast cancer 2 | -1.35 | -1.34 |
| Brms1 | breast cancer metastasis-suppressor 1 | -1.18 | -1.34 |
| Calr | calreticulin | -1.26 | -1.31 |
| Ccnb2 | cyclin B2 | -1.24 | -1.16 |
| Ccng2 | cyclin G2 | 1.23 | 1.32 |
| Ccnk | cyclin K | 1.21 | 1.23 |
| Cdc25c | cell division cycle 25 homolog C (S. cerevisiae) | -1.09 | -1.30 |
| Cdc27 | cell division cycle 27 homolog (S. cerevisiae) | 1.41 | 1.31 |
| Cdc42 | cell division cycle 42 homolog (S. cerevisiae) | 1.34 | 1.50 |
| Cdca1 | cell division cycle associated 1 | 1.24 | 1.50 |
| Cdca5 | cell division cycle associated 5 | 1.18 | 1.30 |
| Cdca8 | cell division cycle associated 8 | -1.24 | -1.11 |
| Cdk5rap3 | CDK5 regulatory subunit associated protein 3 | -1.24 | -1.23 |
| Cetn1 | centrin 1 | 1.46 | 1.31 |
| Cit | citron | 1.20 | 1.35 |
| Cks2 | CDC28 protein kinase regulatory subunit 2 | 1.29 | 1.36 |
| Cul3 | cullin 3 | 1.28 | 1.18 |
| Dhcr24 | 24-dehydrocholesterol reductase | 1.50 | 1.43 |
| Dnajc2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -1.42 | -1.23 |
| Fzr1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 1.44 | 1.39 |
| Gspt1 | G1 to S phase transition 1 | 1.37 | 1.31 |
| Hells | helicase, lymphoid specific | 1.43 | 1.46 |
| Incenp | inner centromere protein | 1.17 | 1.29 |
| Kif20a | kinesin family member 20A | 1.54 | 1.41 |
| Macf1 | microtubule-actin crosslinking factor 1 | 1.16 | 1.49 |
| Mad2l2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 1.19 | 1.27 |
| Mphosph6 | M phase phosphoprotein 6 | 1.30 | 1.26 |
| Mtus1 | mitochondrial tumor suppressor 1 | -1.22 | -1.19 |
| Nasp | nuclear autoantigenic sperm protein (histone-binding) | 1.34 | 1.38 |
| Nek4 | NIMA (never in mitosis gene a)-related expressed kinase 4 | 1.31 | 1.37 |
| Pin1 | protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 | 1.31 | 1.26 |
| Ppp3ca | protein phosphatase 3, catalytic subunit, alpha isoform | -1.19 | -1.22 |
| Pten | phosphatase and tensin homolog | 1.32 | 1.31 |
| Rad17 | RAD17 homolog (S. pombe) | 1.22 | 1.27 |
| Ranbp1 | RAN binding protein 1 | -1.24 | -1.23 |
| Rbm5 | RNA binding motif protein 5 | 1.34 | 1.39 |
| Sgol1 | shugoshin-like 1 (S. pombe) | 1.26 | 1.20 |
| Smarcb1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 1.27 | 1.33 |
| Sycp3 | synaptonemal complex protein 3 | 1.34 | 1.30 |
| Tacc3 | transforming, acidic coiled-coil containing protein 3 | 1.31 | 1.34 |
| Tipin | timeless interacting protein | -1.22 | -1.24 |
| Trrap | transformation/transcription domain-associated protein | -1.26 | -1.22 |
| Tubb6 | tubulin, beta 6 | -1.33 | -1.44 |
| Ube2i | ubiquitin-conjugating enzyme E2I | 1.17 | 1.30 |
| Zw10 | ZW10 homolog (Drosophila), centromere/kinetochore protein | 1.23 | 1.30 |
46 differentially regulated genes regarding the cell cycle process. Results are presented as average gene expression ratios between exposed and control samples.