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. 2010 Jun 17;6(6):e1000968. doi: 10.1371/journal.ppat.1000968

Figure 4. Inhibition of invasion of P. falciparum strains HB3, 3D7, and Dd2NM.

Figure 4

HB3 invasion of neuraminidase-treated cells was least affected by monoclonal and polyclonal antibodies against CR1. Monoclonal antibodies were used at 4 µg/ml. Fab fragments were used at 8 µg/ml and purified proteins were used at 50 µg/ml. Numbers above bars are P values for the comparison with the no-inhibitor control using Dunnett's pairwise multiple comparison t test, taking into account matching by experiment date. Bars represent means ± standard deviations. Alpha-2-mac = α-2-macroglobulin. Invasion rates for untreated erythrocytes with no inhibitor ranged from 3% to 37%.