Table 3.
Cephalosporin and carbapenem susceptibility and MIC data from KPC+ isolates
All isolates were K. pneumoniae and categorized as ESBL+ using the Phoenix system.
| Isolate no. | DD interpretation* | MIC (μg ml−1)† | Phenotype‡ | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Atm | Ctt | Cpd | Ctx | Caz | Cro | Fep | Ipm | Mem | ||
| 101 | R | R | R | R | R | >32 | >16 | >8 | >8 | ESBL+AmpC |
| 107 | R | S | R | S | I | 32 | 2 | <=1 | <=1 | ESBL |
| 117 | I | S | R | S | I | 32 | 2 | 8 | <=1 | ESBL |
| 118 | R | R | R | R | R | >32 | 4 | <=1 | <=1 | ESBL+AmpC |
| 123 | R | S | R | R | R | >32 | >16 | <=1 | 4 | ESBL+AmpC |
| 155 | R | S | R | R | R | >32 | >16 | 4 | >8 | ESBL+AmpC |
| 167 | R | R | R | R | R | >32 | >16 | >8 | >8 | ESBL+AmpC |
| 171 | R | S | R | I | R | >32 | 8 | <=1 | <=1 | ESBL |
*Interpretations based on zone size using CLSI criteria. S, Susceptible; I, intermediate susceptibility; R, resistant. Atm, aztreonam; Ctt, cefotetan; Cpd, cefpodoxime; Ctx, cefotaxime; Caz, ceftazidime.
†MICs were determined by the Phoenix system. Bold indicates resistance and underlining indicates intermediate susceptibility according to CLSI criteria. Cro, Ceftriaxone; Fep, cefepime; Ipm, imipenem; Mem, meropenem.
‡Phenotypes were determined by DD testing as described in the text.