Table 2.

Comparison of the number of organisms in the WT strain MAC 104 and the other STM clones at several time points following infection of mice

C57BL/6 mice were infected intravenously and their spleens were harvested at 24 h, and at weeks 1, 3 and 5, for quantification of the bacterial load.

Clone	No. of c.f.u. per organ
	24 h	1 week	3 weeks	5 weeks
STM1	6.7±0.3×106	6.7±0.4×106	6.1±0.4×105*	5.2±0.3×104*
STM2	6.1±0.3×106	6.5±0.4×106	6.0±0.2×106	4.9±0.2×103*
STM3	5.5±0.5×106	2.3±0.2×106	1.2±0.1×106*	8.6±0.4×105*
STM4	5.6±0.4×106	3.2±0.3×106	2.0±0.2×106*	1.4±0.3×106*
STM5	3.8±0.2×106	1.1±0.2×106*	1.5±0.1×106	9.4±0.7×105*
STM6	2.3±0.9×106	1.1±0.7×106*	8.3±0.6×105*	8.1±0.5×105*
STM8	1.6±0.2×106	1.8±0.6×106*	1.8±0.4×106	1.9±0.3×105*
STM10	3.2±0.4×106	1.1±0.3×106*	2.0±0.4×106	7.3±0.3×104*
STM11	5.1±0.3×106	2.7±0.4×106	8.5±0.3×105*	5.3±0.6×104*
WT (MAC 104)	1.9±0.2×106	3.8±0.2×106	1.3±0.2×107	4.6±0.4×107

*P<0.05 compared with the WT MAC 104 at the same time point.