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TEM micrograph of a capillary found in diseased human liver, fixed by injection of fixative into a wedge biopsy. The thin endothelial lining contains fenestrae, closed by a diaphragm. Underneath the endothelium, one can observe a continuous basal lamina. Fenestrae in this type of capillary are about 60 nm in diameter. It is supposed that transport from this capillary to the tissue is hampered by the structures mentioned. Magnification 28 500 ×.
