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. Author manuscript; available in PMC: 2011 May 27.
Published in final edited form as: J Med Chem. 2010 May 27;53(10):4248–4258. doi: 10.1021/jm100245q

Figure 8.

Figure 8

Effect of compound 4l on endothelial cell shape in cultured HUVECs (top panels) and chick aortic vascular sprouts (lower panels). Cells or aortic arches from 14-day chick embryos were treated with 4l and analyzed by confocal microscopy. The left-hand panels are cells prior to compound addition, and the right-hand panels show cells before and after 30 min of treatment with 10 µM 4l. In the lower panels the arrows indicate the disruption of the aortic vascular sprout induced by drug treatment.