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. Author manuscript; available in PMC: 2010 Jun 18.
Published in final edited form as: Cell Cycle. 2008 Oct 12;7(19):3083–3090. doi: 10.4161/cc.7.19.6778

Figure 2.

Figure 2

let-7 suppressors are enriched for factors involved in RNA and protein metabolism. Genes involved in RNA and protein metabolism are enriched among the suppressors of the let-7(n2853) mutation. Indicated are the distributions across functional classes of genes causing suppression of the let-7(n2853)-associated lethality (left chart) or visible phenotypes in otherwise wild-type animals (right chart; assembled from data in ref. 29). Assignments to functional classes are from Wormbase Release WS188. Where gene assignments had changed from those used by Fraser et al., their data were adjusted accordingly. Note that both studies used an identical RNAi library.