Figure 6. Silencing of Nox4 in the PVN ameliorates peri-infarct apoptosis.
Summary of densitometry analysis of 200-, 400-, and 600-basepair DNA fragments (normalized to sham, n=6) isolated from peri-infarct tissue 14 days after MI (n=6) or MI combined with PVN-targeted AdsiGFP (n=6), AdsiNox4 (n=7), AdCu/ZnSOD (n=9), or AdLacZ (n=8). *p<0.05 vs. Sham; †p<0.05 vs. MI alone, MI+Ad-siGFP, or MI+Ad-LacZ; n.s., not significant.