Figure 5.
Expression of antiapoptotic (a) and proapoptotic (b) proteins. Cells were cultured in the absence (−) or the presence (+) of AVN944 for 2 days. (a) The expression of the indicated Bcl-2 family of antiapoptotic proteins, XIAP (inhibitor of apoptotic proteins) and survivin was analyzed by the western blot method as described. (b) The expression of proapoptotic proteins was analyzed as described in (a). GAPDH is indicated as the loading control. Experiments were repeated 3 times, and representative blots are presented.