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. Author manuscript; available in PMC: 2010 Jun 18.
Published in final edited form as: Int J Cancer. 2008 Nov 15;123(10):2294–2302. doi: 10.1002/ijc.23788

Figure 6.

Figure 6

Cell viability of AVN944-differentiated DU145 and PC-3 cells treated with TRAIL (a) and TRAIL-induced apoptosis in AVN944-differentiated PC-3 and DU145 cells (b). (a) DU145 and PC-3 cells were treated with AVN944 for 3 days. At the end of treatment, cells were subjected to TRAIL for 1 d. Cell viability was determined by the MTS assay. Bars indicate SD. (b) DU145 and PC-3 cells were treated with AVN944 for 3 days. At the end of treatment, cells were subjected to TRAIL for 6 hr. Cell lysates were analyzed for the expression of apoptotic markers, including cleaved caspase-9, caspase-3 and PARP. Experiments were repeated 3 times, and typical results are presented. C, control; T, TRAIL; A, AVN944; A+T, AVN944+TRAIL.