Table 2.

Gene set enrichment analysis of changes in gene expression between WG patients and controls

Gene Set Name	Major Pathway	Gene Set Size	GSEA Normalized Enrichment Score	GSEA nominal p-value	Estimated FDR q-value
VERHAAK_AML_NPM1_MUT_VS_WT_UP	Leukemia	154	2.80	< 0.001	0
APPEL_IMATINIB_UP	Leukemia	28	2.76	< 0.001	0
ROSS_MLL_FUSION	Leukemia	70	2.73	< 0.001	0
LIAN_MYELOID_DIFF_GRANULE	Myeloid Differentiation	19	2.61	< 0.001	0
HSA01032_GLYCAN_STRUCTURES_DEGRADATION	N/A	25	2.58	< 0.001	0
PARK_RARALPHA_MOD	Myeloid Differentiation	54	2.55	< 0.001	0
MARTINELLI_IFNS_DIFF	Myeloid Differentiation	22	2.54	< 0.001	0
LAL_KO_3MO_UP	N/A	38	2.43	< 0.001	0
HSA04610_COMPLEMENT_AND_COAGULATION_CASCADES	N/A	36	2.38	< 0.001	3.85E-04
CARIES_PULP_UP	N/A	174	2.37	< 0.001	4.17E-04