Table 2.
IGF 2 expression in LMP tumors and epithelial ovarian carcinoma (EOC)
| Variable | LMP tumors (36) |
EOC (79) |
Totals (115) |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IGF2-Low N | (%) | IGF2-High N | (%) | p | IGF2-Low N | (%) | IGF2-High N | (%) | p | IGF2-Low N | (%) | IGF2-High N | (%) | p | |
| Age | 1.000 | 0.873 | 0.335 | ||||||||||||
| ≤ 50 years | 17 | 60.7 | 5 | 62.5 | 9 | 28.1 | 14 | 29.8 | 26 | 43.3 | 19 | 34.5 | |||
| > 50 years | 11 | 39.3 | 3 | 37.5 | 23 | 71.9 | 33 | 70.2 | 34 | 56.7 | 36 | 65.5 | |||
| Race/Ethnicity | 0.544 | 0.339 | 0.166 | ||||||||||||
| Non-Hispanic White | 15 | 53.6 | 6 | 75.0 | 12 | 37.5 | 24 | 51.1 | 27 | 45.0 | 30 | 54.6 | |||
| Hispanic | 10 | 35.7 | 1 | 12.5 | 14 | 43.8 | 14 | 29.8 | 24 | 40.0 | 15 | 27.3 | |||
| American Indian | 1 | 3.6 | 0 | 0.0 | 1 | 3.1 | 0 | 0.0 | 6 | 10.0 | 10 | 18.2 | |||
| Black | 1 | 3.6 | 1 | 12.5 | 5 | 15.6 | 9 | 19.1 | 2 | 3.3 | 0 | 0.0 | |||
| Asian | 1 | 3.6 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 1 | 1.7 | 0 | 0.0 | |||
| FIGO Stage | 0.028 | 0.124 | <0.001 | ||||||||||||
| I | 27 | 96.4 | 5 | 62.5 | 12 | 37.5 | 12 | 25.5 | 39 | 65.0 | 17 | 30.9 | |||
| II | 0 | 0.0 | 2 | 25.0 | 4 | 12.5 | 3 | 6.4 | 4 | 6.7 | 5 | 9.1 | |||
| III | 1 | 3.6 | 1 | 12.5 | 15 | 46.9 | 23 | 48.9 | 16 | 26.7 | 24 | 43.6 | |||
| IV | 0 | 0.0 | 0 | 0.0 | 1 | 3.1 | 9 | 19.1 | 1 | 1.7 | 9 | 16.4 | |||
| Histology | 0.055 | 0.664 | 0.011 | ||||||||||||
| Serous | 10 | 35.7 | 7 | 87.5 | 17 | 53.1 | 27 | 57.4 | 27 | 45.0 | 34 | 61.8 | |||
| Mucinous | 16 | 57.1 | 1 | 12.5 | 6 | 18.8 | 5 | 10.6 | 22 | 36.7 | 6 | 10.9 | |||
| Endometrioid | 0 | 0.0 | 0 | 0.0 | 3 | 9.4 | 3 | 6.4 | 3 | 5.0 | 3 | 5.5 | |||
| Other | 2 | 7.1 | 0 | 0.0 | 6 | 18.8 | 12 | 25.5 | 8 | 13.3 | 12 | 21.8 | |||
| Tumor Grade | N/A | 0.933 | 0.003 | ||||||||||||
| 0 | 28 | 100.0 | 8 | 100.0 | 0 | 0.0 | 0 | 0.0 | 28 | 46.7 | 8 | 14.6 | |||
| 1 | 0 | 0.0 | 0 | 0.0 | 5 | 15.6 | 7 | 14.9 | 5 | 8.3 | 7 | 12.7 | |||
| 2 | 0 | 0.0 | 0 | 0.0 | 7 | 21.9 | 12 | 25.5 | 7 | 11 . 7 | 12 | 21.8 | |||
| 3 | 0 | 0.0 | 0 | 0.0 | 20 | 62.5 | 28 | 59.6 | 20 | 33.3 | 28 | 50.9 | |||
| Total | 28 | 8 | 32 | 47 | 60 | 55 | |||||||||
IGF2-Low, H-score≤105; IGF2-High, H-score>105; N/A, not applicable