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Liver histology from B6 control and P-gp deficient piroxicam treated animals. B6 (A), B6.mdr1a−/− (B) and piroxicam treated B6 wild type animals demonstrated no significant liver histological changes or inflammation, while B6.mdr1a−/− piroxicam treated animals showed severe liver inflammation. Images captured at 400X magnification. Bar=50µm
