Table 2.
Association of isolated systolic hypertension with incident heart failure
| Outcomes | Rate, per 10,000 person-years follow-up (% events) |
Rate difference* (per 10,000 person-years) | Hazard ratio (95% confidence interval) | P value | |
|---|---|---|---|---|---|
| Isolated systolic hypertension | |||||
| No | Yes | ||||
| Before matching (n=5248) | n=3248 | n=2000 | |||
| Unadjusted | 164 (14) | 277 (22) | + 113 | 1.72 (1.51–1.97) | <0.0001 |
| Multivariable-adjusted | – | – | – | 1.35 (1.18–1.56) | <0.0001 |
| Propensity-adjusted | – | – | – | 1.22 (1.04–1.44) | 0.016 |
| After matching (n=2520) | n=1260 | n=1260 | |||
| Incident heart failure | 194 (16) | 242 (20) | + 48 | 1.26 (1.04–1.51) | 0.016 |
*
Absolute rate differences were calculated by subtracting the rates of new-onset heart failure in the no isolated systolic hypertension group from those in the isolated systolic hypertension group (before values were rounded).