Table 2.
Impact of COMT genotype on fMRI BOLD activation
| Region of Interest | Genotype (df = 1) | |||
|---|---|---|---|---|
|
Met/Met (Mean Z value/SD) |
Val carriers (Mean Z value/SD) |
F | p | |
| ACC | 1.69/1.75 | 0.55/1.05 | 9.447 | 0.003 |
| Insula | 2.29/1.88 | 1.40/1.08 | 5.136 | 0.027 |
| parietal operculum (containing S2) | 2.13/1.75 | 1.36/0.94 | 4.677 | 0.035 |
| Amygdalae | 1.09/1.48 | 0.52/0.85 | 3.507 | 0.066 |
Analyses of variance (ANOVAs) with genotype as factor and mean Z values in regions of interest as dependent variables.
df = degrees of freedom; ACC = anterior cingulate cortex; S2 = secondary somatosensory cortex; SD = standard deviation