Table 1.
Results of microarray analysis for 5 genes within 1 Mb from rs11249433 in the 1p11.2 region.
| Gene/SNP | Position, bp+ | rs11249433 | N | Fold* | 95%CI | p-value* |
|---|---|---|---|---|---|---|
| ADAM30 | chr1: 120,237,679 - 120,240,636 | AA | 35 | 1.00 | 0.90 - 1.11 | 0.378 |
| AG | 41 | 1.06 | 0.96 - 1.16 | |||
| GG | 13 | 0.93 | 0.80 - 1.09 | |||
| NOTCH2 | chr1: 120,279,260 - 120,413,799 | AA | 41 | 1.00 | 0.85 - 1.18 | 0.054 |
| AG | 45 | 1.28 | 1.10 - 1.50 | |||
| GG | 17 | 1.16 | 0.91 - 1.46 | |||
| NOTCH2NL | chr1: 120,338,694 - 120,398-362 | AA | 41 | 1.00 | 0.75 - 1.33 | 0.038 |
| chr1: 143,920,468 - 144,009,723 | AG | 47 | 0.64 | 0.49 - 0.83 | ||
| GG | 19 | 0.70 | 0.47 - 1.04 | |||
| FAM72B | chr1: 120,640,935 - 120,657,204 | AA | 41 | 1.00 | 0.68 - 1.47 | 0.218 |
| AG | 47 | 0.76 | 0.53 - 1.10 | |||
| GG | 19 | 0.59 | 0.35 - 1.00 | |||
| SRGAP2 | chr1: 120,808,675 - 120,832,674 | AA | 41 | 1.00 | 0.82 - 1.21 | 0.652 |
| chr1: 204,582,823 - 204,648,014 | AG | 48 | 1.03 | 0.86 - 1.24 | ||
| GG | 19 | 0.89 | 0.68 - 1.17 | |||
| rs11249433 | chr1: 120,982,136 |
+ Based on the UCSC genome browser on Human Mar. 2006 assembly (hg18).
*Generalized linear model adjusted for age, ER and PR status.