Table 2.
Age-adjusted OR(95%CI) of dementia and its subtypes in people with subclinical hyperthyroidism compared to normal thyroid function.
| Model | Odds ratio (95% CI) |
|
|---|---|---|
| All (n = 33) subclinical hyperthyroidism | ||
| Any type of dementia (n = 49) |
Crude | 3.2 (1.1-9.5) |
| Age-adjusted | 4.1 (1.3-13.1) | |
| Multivariate adjusted* | 4.9 (1.5-15.7) | |
| Alzheimer Disease (n = 19) |
Crude | 1.9 (0.2-14.3) |
| Age-adjusted | 2.1 (0.3-17.3) | |
| Multivariate adjusted* | 2.5 (0.3-20.8) | |
| Vascular dementia (n = 18) |
Crude | 4.3 (1.0-19.6) |
| Age-adjusted | 5.3 (1.1-26.4) | |
| Multivariate adjusted* | 6.7 (1.4-33.1) | |
| Men (n = 10) subclinical hyperthyroidism | ||
| Any type of dementia (n = 16) |
Crude | 7.5 (1.5-38.4) |
| Age-adjusted | 8.0 (1.5-43.4) | |
| Multivariate adjusted* | 8.1 (1.5-44.6) | |
| Alzheimer Disease (n = 5) |
Crude | 11.9 (1.2-117.0) |
| Age-adjusted | 12.4 (1.2-128.4) | |
| Multivariate adjusted* | 11.6 (1.1-120.7) | |
| Vascular dementia (n = 9) |
Crude | 5.9 (0.7-52.0) |
| Age-adjusted | 6.1 (0.7-56.3) | |
| Multivariate adjusted* | 5.8 (0.6-54.4) | |
| Women (n = 23) subclinical hyperthyroidism) | ||
| Any type of dementia (n = 33) |
Crude | 1.9 (0.4-8.5) |
| Age-adjusted | 2.6 (0.5-13.6) | |
| Multivariate adjusted* | 3.4 (0.7-17.3) | |
| Vascular dementia (n = 9) |
Crude | 3.7 (0.4-30.6) |
| Age-adjusted | 5.0 (0.5-55.0) | |
| Multivariate adjusted* | 9.2 (0.9-96.4) | |
*Multivariate adjusted include adjustment for age and body-mass index.