Table 3.

Intracohort (rows) comparisons of past-year prevalence of prescription opioid-use disorder

	Age ranges (n)		Disorder, % [95% CI]
Birth year	NLAES 1991–1992	NESARC 2001–2002	NLAES 1991–1992	NESARC 2001–2002	Intracohort differencea
Past–year disorder in the overall population
1974–1983	—	18–27 (7,168)	—	0.6 [0.4, 0.9]	—
1964–1973	18–27 (7,746)	28–37 (8,527)	0.3 [0.2, 0.5]	0.3 [0.2, 0.4]	−13%
1954–1963	28–37 (10,221)	38–47 (8,840)	0.08 [0.03, 0.1]	0.5 [0.3, 0.7]	488%***
1944–1953	38–47 (7,820)	48–57 (6,862)	0.1 [0.04, 0.2]	0.2 [0.05, 0.3]	25%
1934–1943	48–57 (5,056)	—	0.04 [0.01, 0.08]	—	—
Total (1944–1973)	38–47 (7,820)	28–57 (24,229)	0.2 [0.1, 0.2]	0.3 [0.2, 0.4]	55%*
Past–year disorder among lifetime users
1974–1983	—	18–27 (255)	—	15.8 [10.0, 21.7]	—
1964–1973	18–27 (269)	28–37 (266)	9.8 [5.4, 14.2]	8.0 [4.2, 11.8]	−18%
1954–1963	28–37 (398)	38–47 (332)	1.8 [0.6, 3.0]	11.4 [6.8, 15.9]	533%***
1944–1953	38–47 (237)	48–57 (177)	4.4 [1.4, 7.3]	6.1 [2.1, 10.0]	38.6%
1934–1943	48–57 (57)	—	4.0 [0.3, 7.6]	—	—
Total (1944–1973)	18–47 (692)	28–57 (775)	4.8 [3.2, 6.4]	9.1 [6.5, 11.6]	89.6%**

Notes: NLAES = National Longitudinal Alcohol Epidemiologic Survey; NESARC = National Epidemiologic Study on Alcohol and Related Conditions.

^aDifference between 2001-2002 (NESARC) and 1991-1992 (NLAES) past-year prevalence estimates for a given birth cohort.

^*p <.05;

^**p <.01;

^***p < .001.