Figure 7. Basolateral (bl) adrenaline-induced ion transport effects in distal colonic mucosa of NMRI mice from untreated controls and propranolol-incubated (1 μm) tissues.

A and B, original Ussing chamber recordings in untreated controls (A) and in propranolol-incubated tissues (B). C, summary of calculated adrenaline-induced I_sc effects in the absence and presence of propranolol. From each mouse two distal colonic, directly proximate mucosa pieces served as the paired control (* indicates statistical significance between groups). The connecting lines between the data points indicate data from the same mouse. Note that adrenaline-induced electrogenic ion transport effects were completely absent with propranolol. The horizontal bars indicate mean values.