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. Author manuscript; available in PMC: 2011 May 28.
Published in final edited form as: Cell. 2010 May 20;141(5):884–896. doi: 10.1016/j.cell.2010.03.054

Figure 7. Regulatory motifs in the c-Fos expression network and emerging differential, long-term transcription factor expression.

Figure 7

A. DUSP negative feedback superimposed onto the CFL. B. The CFL cascade structure of c-Fos regulation wherein the fast, nuclear inner CFL is contained within the slow, cytoplasmic outer CFL. C. The overall network structure which includes the cascade CFL embedded into the transcriptional negative feedback loops. D. Venn diagrams showing the number of common differentially expressed TFs between the EGF and HRG responses. The EGF (left - blue) and HRG (right - red) sets correspond to the number of differentially expressed gene probes that were identified as transcription factors by query to the gene ontology database. See also Fig. S5.