. Author manuscript; available in PMC: 2010 Jun 21.

Published in final edited form as: Synlett. 2009 May;8(2009):1189–1207. doi: 10.1055/s-0029-1216654

Table 10.

Formation of quaternary steocenters from aliphatic aldehydes tethered to different Michael acceptors. graphic file with name nihms-199310-t0145.jpg

Entry	Substrate	Product	Catalyst	Yield %	ee%

1	181 E-isomer	182 R = 4-Py	35	85	96
2	183 Z-isomer	183 R = p-NO₂Ph	35	50	56
3			35	85	96
4			35	90	84
5			35	81	95
6			35	63	99
7			35	71	98
8			35	0	--
9			35	78	65
9			40	86	90^a
10			40	98	80^a
11			35	65	95
12			35	0	--
12			40	0	--

Opposite antipode was obtained.