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. Author manuscript; available in PMC: 2010 Jun 21.
Published in final edited form as: Synlett. 2009 May;8(2009):1189–1207. doi: 10.1055/s-0029-1216654

Table 12.

Asymmetric synthesis of hydrobenzofuranones via the intramolecular Stetter reaction graphic file with name nihms-199310-t0189.jpg

Entry R Substrate Product Yield % ee%
1 Me 247 248 90 92
2 Et 248 249 86 94
3 i-Pr 250 251 87 94
4 t-Bu 252 253 86 94
5 Ph 254 255 87 88
6 4-BrPh 256 257 78 85
7 CH2OAc 258 259 86 83
8 CH2CH2OMe 260 261 86 82
9 CH2CH2CO2Me 262 263 94 87